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GGTC German Gene Trap Consortium


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Araki, K., et al., and (1999):

Exchangeable gene trap using the Cre/mutated lox system.
Cell Mol Biol (Noisy-le-grand). 45(5): p. 737-50.



Baker RK, Haendel MA, Swanson BJ, Shambaugh JC, Micales BK, Lyons GE. (1997):

In vitro preselection of gene-trapped embryonic stem cell clones for characterizing novel developmentally regulated genes in the mouse.
Dev Biol. May 15; 185(2): 201-14.



Cecconi F, Alvarez-Bolado G, Meyer BI, Roth KA, Gruss P. (1998):

Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development.
Cell. Sep 18; 94(6): 727-37.




Chowdhury, K., et al., (1997):

Evidence for the stochastic integration of gene trap vectors into the mouse germline.
Nucleic Acids Res, 1997. 25(8): p. 1531-6.



Couldrey, C., et al., (1999):

A retroviral gene trap insertion into the histone 3.3A gene causes partial neonatal lethality, stunted growth, neuromuscular deficits and male sub-fertility in transgenic mice.
Hum Mol Genet, 1999. 8(13): p. 2489-95.



Floss T. and Wurst W. (2001):

Functional genomics by gene-trapping in embryonic stem cells. In: Embryonic Stem Cells Models to Study Lineage Specific Differentiation in vitro: Methods and Protocols.
Humana Press, in press.



Forrester LM, Nagy A, Sam M, Watt A, Stevenson L, Bernstein A, Joyner AL, Wurst W. (1996):

An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro.
Proc Natl Acad Sci U S A. Feb 20;93(4):1677-82.




Friedrich GA, Hildebrand JD, Soriano P. (1997):

The secretory protein Sec8 is required for paraxial mesoderm formation in the mouse.
Dev Biol. Dec 15;192(2):364-74.



Friedrich, G. and P. Soriano (1991).

"Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice."
Genes Dev 5(9): 1513-23.



Gasca S, Hill DP, Klingensmith J, Rossant J. (1995):

Characterization of a gene trap insertion into a novel gene, cordon-bleu, expressed in axial structures of the gastrulating mouse embryo.
Dev Genet. 1995;17(2):141-54.




Gossler, A., et al.(1989):

Mouse embryonic stem cells and reporter constructs to detect developmentally regulated genes.
Science, 1989. 244(4903): p. 463-5.



Hartl, D. L. and H. Ochman (1994).

"Inverse polymerase chain reaction."
Methods Mol Biol 31: 187-96.



Hicks GG, Shi EG, Li XM, Li CH, Pawlak M, Ruley HE (1997):

Functional genomics in mice by tagged sequence mutagenesis.
Nat Genet. Aug;16(4):338-44.




Hildebrand JD, Soriano P. (1999):

Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice.
Cell. Nov 24;99(5):485-97.



Hill, D.P. and W. Wurst (1993):

Gene and enhancer trapping: mutagenic strategies for developmental studies.
Curr Top Dev Biol, 1993. 28: p. 181-206.



Ishida, Y. and P. Leder, RET (1999) :

a poly A-trap retrovirus vector for reversible disruption and expression monitoring of genes in living cells.
Nucleic Acids Res, 1999. 27(24): p. e35.




Mainguy G, Luz Montesinos M, Lesaffre B, Zevnik B, Karasawa M, Kothary R, Wurst W, Prochiantz A, Volovitch M. (2000):

An induction gene trap for identifying a homeoprotein-regulated locus.
Nat Biotechnol. Jul;18(7):746-749.



McClive P, Pall G, Newton K, Lee M, Mullins J, Forrester L. (1998):

Gene trap integrations expressed in the developing heart: insertion site affects splicing of the PT1-ATG vector.
Dev Dyn. Jun;212(2):267-76.



Salminen, M., B.I. Meyer, and P. Gruss (1998):

Efficient poly A trap approach allows the capture of genes specifically active in differentiated embryonic stem cells and in mouse embryos.
Dev Dyn, 1998. 212(2): p. 326-33.




Sam M, Wurst W, Kluppel M, Jin O, Heng H, Bernstein A. (1998):

Aquarius, a novel gene isolated by gene trapping with an RNA-dependent RNA polymerase motif.
Dev Dyn. Jun;212(2):304-17.



Skarnes WC, Auerbach BA, Joyner AL. (1992):

A gene trap approach in mouse embryonic stem cells: the lacZ reported is activated by splicing, reflects endogenous gene expression, and is mutagenic in mice.
Genes Dev. Jun;6(6):903-18.



Skarnes WC, Moss JE, Hurtley SM, Beddington RS. (1995):

Capturing genes encoding membrane and secreted proteins important for mouse development.
Proc Natl Acad Sci U S A. Jul 3;92(14):6592-6.




Stoykova A, Chowdhury K, Bonaldo P, Torres M, Gruss P. (1998):

Gene trap expression and mutational analysis for genes involved in the development of the mammalian nervous system.
Dev Dyn. Jun;212(2):198-213.



Takeuchi T, Yamazaki Y, Katoh-Fukui Y, Tsuchiya R, Kondo S, Motoyama J, Higashinakagawa T. (1995):

Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation.
Genes Dev. May 15;9(10):1211-22.



Townley, D.J., et al., (1997)

Rapid sequence analysis of gene trap integrations to generate a resource of insertional mutations in mice.

Genome Res, 1997. 7(3): p. 293-8.




Triglia, T. (2000).

"Inverse PCR (IPCR) for obtaining promoter sequence."
Methods Mol Biol 130: 79-83.



von Melchner H, DeGregori JV, Rayburn H, Reddy S, Friedel C, Ruley HE. (1992):

Selective disruption of genes expressed in totipotent embryonal stem cells.
Genes Dev. Jun;6(6):919-27.



Voss AK, Thomas T, Gruss P. (1998):

Compensation for a gene trap mutation in the murine microtubule-associated protein 4 locus by alternative polyadenylation and alternative splicing.
Dev Dyn. Jun;212(2):258-66.




Wiles MV, Vauti F, Otte J, Fuchtbauer EM, Ruiz P, Fuchtbauer A, Arnold HH, Lehrach H, Metz T, von Melchner H, Wurst W. (2000):

Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.
Nat Genet. Jan;24(1):13-4.



Wurst W and Gossler A (2000):

Gene trap strategies in ES cells. In: A. Joyner (ed.): "Gene Targeting", A practical approach, 2nd edition.
Oxford University Press.



Wurst W, Rossant J, Prideaux V, Kownacka M, Joyner A, Hill DP, Guillemot F, Gasca S, Cado D, Auerbach A, et al. (1995):

A large-scale gene-trap screen for insertional mutations in developmentally regulated genes in mice.
Genetics. Feb; 139(2):889-99.



Xiong JW, Battaglino R, Leahy A, Stuhlmann H. (1998):

Large-scale screening for developmental genes in embryonic stem cells and embryoid bodies using retroviral entrapment vectors.
Dev Dyn. Jun; 212(2):181-97




Yoshida M, Yagi T, Furuta Y, Takayanagi K, Kominami R, Takeda N, Tokunaga T, Chiba J, Ikawa Y, Aizawa S. (1995):

A new strategy of gene trapping in ES cells using 3'RACE. Transgenic Res. 1995 Jul;4(4):277-87.



Zambrowicz, B.P., et al.,

Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells.
Nature, 1998. 392(6676): p. 608-11.